منابع مشابه
[5-Fluorouracil-induced reticular hyperpigmentation].
superficial dermis with occasional melanophages (Figure 3). The patient continued to receive cycles of chemotherapy, with no observed increase in pigmentation, until completing the treatment after 11 infusions. Five months after the last cycle of chemotherapy and 8 months after the appearance of the hyperpigmentation, no pigmentation was seen on the palms of the hands, and the reticular pigment...
متن کامل5-fluorouracil-induced coronary vasospasm.
BACKGROUND Cardiotoxicity is a rare but well-documented adverse effect of 5-fluorouracil (5-FU). The underlying cause of this side effect of 5-FU is uncertain. METHODS We present a case report of a 63-year-old man treated for metastatic colon cancer who experienced chest pain while being treated with the FOLFIRI regimen. This case report documents coronary artery spasm on catheterization obse...
متن کاملA case of 5-fluorouracil induced encephalopathy.
Patients with reduced dihydropyrimidine dehydrogenase (DPD) activity are at risk for experiencing serious adverse effects following 5-fluorouracil (5-FU) based chemotherapy. Neurotoxicity is considered an extremely rare side effect of 5-FU. We report here on an unusual case of 5-FU induced encephalopathy. A 38-year-old woman with advanced gastric carcinoma was treated with adjuvant chemotherapy...
متن کامل5-Fluorouracil (5-FU) Induced Acute Toxic Leukoencephalopathy
This is a 57-year-old right-handed male with a history of locally advanced esophageal adenocarcinoma, who presented with confusion and speech changes. Patient received 5-Fluorouracil (5-FU) and cisplatin four days prior to presentation, which was complicated by very poor oral intake on day 2 of therapy. On the day of presentation, he was confused and his speech was slurred. The remainder of the...
متن کاملCarcinoembryonic Antigen Expression and Resistance to Radiation-and 5-Fluorouracil-Induced Apoptosis and Autophagy
Understanding the mechanism of tumor resistance is critical for cancer therapy. In this study, we investigated the effect of carcinoembryonic antigen (CEA) overexpression on UV-and 5-fluorouracil (5-FU)-induced apoptosis and autophagy in colorectal cancer cells. We used histone deacetylase (HDAC) inhibitor, NaB and DNA demethylating agent, 5- azacytidine (5-AZA) to induce CEA expression in HT29...
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ژورنال
عنوان ژورنال: Case Reports
سال: 2011
ISSN: 1757-790X
DOI: 10.1136/bcr.02.2011.3883